I have tried Symlin and Victoza. Both tend to cause weight loss, and are generally used by Type 1s (for Victoza, as off-label use) to help level out postprandial blood sugars. If I used a pump and CGM, I would have stuck w/ Symlin -- but b/c I use MDI and a CGM, I ultimately had a strong preference for Victoza. (Re weight loss, there tends to be quite a bit at first - which for me was a problem -- but that effect often decreases over time for users.) If you have any specific questions, please feel free to ask.